Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DGUA_6G012887Blast:Lysosomal aspartic protease; Belongs to the peptidase A1 family. (402 aa)    
Predicted Functional Partners:
DGUA_6G020116
Blast:Cathepsin B; Belongs to the peptidase C1 family.
   
 0.919
DGUA_6G004579
Blast:Lysosome-associated membrane glycoprotein 1.
   
 
 0.860
DGUA_6G001765
Blast:Cathepsin L; Belongs to the peptidase C1 family.
   
 0.837
DGUA_6G002834
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
      
 0.664
DGUA_6G019397
Uncharacterized protein.
   
  
 0.576
DGUA_6G005039
Blast:Renin receptor.
   
 0.575
DGUA_6G003407
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
      
 0.542
DGUA_6G007023
Battenin.
    
 
 0.533
DGUA_6G017236
Blast:Putative cysteine proteinase CG12163.
   
 0.516
DGUA_6G017235
Blast:Putative cysteine proteinase CG12163; Belongs to the peptidase C1 family.
   
 0.516
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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