Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
DGUA_6G005271CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (493 aa)    
Predicted Functional Partners:
DGUA_6G011259
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
  
 
 0.992
DGUA_6G020431
Blast:Probable cardiolipin synthase.
    
 0.992
DGUA_6G009520
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
     
 0.991
DGUA_6G017468
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
   
 0.793
cn
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
   
 0.791
DGUA_6G017669
Blast:Probable complex I intermediate-associated protein 30, mitochondrial.
     
  0.752
DGUA_6G008721
Blast:Ribonuclease H2 subunit B.
   
    0.742
DGUA_6G002253
Tafazzin family protein; Belongs to the taffazin family.
     
 0.722
DGUA_6G002887
Blast:Cytochrome b5 reductase 4.
      
 0.686
DGUA_6G006851
Blast:Putative phosphatidate phosphatase.
   
 0.681
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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