Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G013859Blast:NAD-dependent histone deacetylase Sir2. (868 aa)    
Predicted Functional Partners:
DGUA_6G015871
Blast:NAD-dependent protein deacetylase Sirt7.
  
 0.998
DGUA_6G013396
Blast:NAD-dependent protein deacetylase Sirt6.
  
0.994
DGUA_6G005217
Nicotinamide-nucleotide adenylyltransferase.
   
 0.994
DGUA_6G020354
NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.
  
 
0.987
DGUA_6G010672
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.985
DGUA_6G020638
Blast:Armadillo segment polarity protein.
   
 0.985
DGUA_6G001311
Blast:NAD kinase.
  
 
 0.980
DGUA_6G007903
Blast:Protein cycle.
    
 0.980
DGUA_6G000371
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.978
DGUA_6G015062
Blast:Purine nucleoside phosphorylase.
    
 0.978
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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