Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DGUA_6G013004Blast:E3 ubiquitin-protein ligase RFWD3. (179 aa)    
Predicted Functional Partners:
DGUA_6G011881
Blast:Ubiquitin-60S ribosomal protein L40.
    
 0.740
DGUA_6G015987
Blast:Protein fem-1 homolog C.
    
 
 0.649
DGUA_6G016960
Blast:PHD and RING finger domain-containing protein 1.
      
 0.646
DGUA_6G013333
Blast:Ubiquitin-40S ribosomal protein S27a.
    
 0.593
DGUA_6G018452
Blast:Relaxin receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.527
DGUA_6G007855
Blast:Large proline-rich protein bag6-A.
    
 
 0.500
DGUA_6G018080
Blast:E3 ubiquitin-protein ligase hyd.
    
 
 0.472
DGUA_6G019054
Blast:Furin-like protease 2; Belongs to the peptidase S8 family.
    
  0.453
DGUA_6G016492
Blast:Furin-like protease 1, isoforms 1/1-X/2; Belongs to the peptidase S8 family.
    
  0.453
DGUA_6G015151
Blast:Polyubiquitin.
    
 0.439
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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