Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G004936Blast:Neutral ceramidase; Belongs to the mitochondrial carrier (TC 2.A.29) family. (689 aa)    
Predicted Functional Partners:
DGUA_6G001188
Prohibitin.
    
 
 0.743
DGUA_6G015781
Blast:Mitochondrial import inner membrane translocase subunit Tim22.
     
 0.681
DGUA_6G001456
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.653
DGUA_6G010262
Blast:NADH dehydrogenase.
      
 0.651
DGUA_6G013998
Blast:Cytochrome c oxidase assembly protein COX11, mitochondrial.
      
 0.634
DGUA_6G012404
Blast:Cytochrome c oxidase subunit 6C.
    
   0.607
DGUA_6G017341
Blast:Polypyrimidine tract-binding protein 1.
      
 0.596
DGUA_6G015930
Blast:Inositol polyphosphate 1-phosphatase.
      
 0.594
DGUA_6G016755
Blast:Argininosuccinate synthase.
      
 0.592
DGUA_6G010491
Blast:Ral GTPase-activating protein subunit beta.
      
 0.556
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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