Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G014087Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (140 aa)    
Predicted Functional Partners:
DGUA_6G017359
Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
  
 0.978
DGUA_6G010052
Uncharacterized protein.
   
    0.760
DGUA_6G004300
Blast:NADH dehydrogenase.
   
   0.533
DGUA_6G014293
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
  
 0.458
DGUA_6G016178
Uncharacterized protein.
   
    0.454
DGUA_6G015040
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
  
 0.449
DGUA_6G006625
Blast:Alsin.
   
  
 0.441
DGUA_6G016370
U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family.
      
 0.440
DGUA_6G002711
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
  
 0.436
DGUA_6G002949
Protein-serine/threonine kinase.
      
 0.436
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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