Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G000653Blast:CCR4-NOT transcription complex subunit 11. (228 aa)    
Predicted Functional Partners:
DGUA_6G003548
Blast:CCR4-NOT transcription complex subunit 1.
    
 0.999
DGUA_6G017272
Blast:CCR4-NOT transcription complex subunit 10 homolog.
    
 0.999
DGUA_6G017923
Blast:Regulator of gene activity.
   
 0.994
DGUA_6G020822
Blast:Cell differentiation protein RCD1 homolog.
   
 0.993
DGUA_6G008146
Blast:CCR4-NOT transcription complex subunit 7.
    
 0.989
DGUA_6G013568
Blast:Regulator of gene activity.
   
 0.984
DGUA_6G017327
Blast:Cell differentiation protein RCD1 homolog.
   
 0.981
DGUA_6G013340
Uncharacterized protein.
     
 0.968
DGUA_6G014140
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 
 0.943
DGUA_6G003847
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 0.941
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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