Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G014209Blast:SUZ domain-containing protein 1. (348 aa)    
Predicted Functional Partners:
DGUA_6G001604
Blast:Serine-threonine kinase receptor-associated protein.
    
   0.812
DGUA_6G000410
Blast:Serine-threonine kinase receptor-associated protein.
    
   0.812
DGUA_6G019706
Blast:Methenyltetrahydrofolate synthase domain-containing protein.
   
    0.787
DGUA_6G006181
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
    0.783
DGUA_6G011449
Blast:U3 small nucleolar RNA-associated protein 15 homolog.
   
    0.782
DGUA_6G002364
Blast:Small integral membrane protein 12-A.
   
   0.779
DGUA_6G017478
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
   
 
  0.752
DGUA_6G010348
Blast:Calpain-D; Belongs to the peptidase C2 family.
   
    0.745
DGUA_6G004177
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
    0.740
DGUA_6G017461
Structural maintenance of chromosomes protein.
   
    0.736
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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