Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G000905Blast:Inhibitor of Bruton tyrosine kinase. (1184 aa)    
Predicted Functional Partners:
DGUA_6G013564
Blast:Cullin-3-A; Belongs to the cullin family.
   
 0.951
DGUA_6G001780
Blast:Ribonuclease P protein subunit p25-like protein.
    
   0.930
DGUA_6G004707
Blast:Eukaryotic initiation factor 4A; Belongs to the DEAD box helicase family.
    
   0.879
DGUA_6G018269
Blast:DnaJ homolog subfamily C member 17.
      
 0.820
DGUA_6G003389
Blast:Cullin homolog 1; Belongs to the cullin family.
   
 0.741
DGUA_6G006658
Blast:Cullin homolog 1; Belongs to the cullin family.
   
 0.741
DGUA_6G006863
Blast:Cysteine string protein.
    
 
 0.669
DGUA_6G000089
Blast:Protein N-terminal glutamine amidohydrolase.
      
 0.643
DGUA_6G008728
Blast:Pleckstrin homology-like domain family B member 2.
      
 0.557
DGUA_6G020550
Blast:Copper-transporting ATPase 1.
      
 0.539
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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