Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G000403Myb_DNA-bind_5 domain-containing protein. (500 aa)    
Predicted Functional Partners:
DGUA_6G014211
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
   
 0.979
DGUA_6G016523
Blast:Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial.
    
 0.764
DGUA_6G016263
Blast:C-1-tetrahydrofolate synthase, cytoplasmic.
   
 0.762
DGUA_6G010270
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.758
DGUA_6G019706
Blast:Methenyltetrahydrofolate synthase domain-containing protein.
     
 0.643
DGUA_6G006142
Blast:Methionyl-tRNA formyltransferase, mitochondrial.
   
 
 0.585
DGUA_6G005199
Blast:Bifunctional purine biosynthesis protein PURH.
    
 0.564
DGUA_6G014562
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
      
 0.479
DGUA_6G020392
Blast:Estradiol 17-beta-dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.415
DGUA_6G014089
Blast:Hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.415
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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