Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G006344Aminopeptidase. (970 aa)    
Predicted Functional Partners:
DGUA_6G007643
Blast:Gamma-glutamylcyclotransferase.
     
  0.972
DGUA_6G006202
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
    
  0.972
DGUA_6G010432
Blast:Glutamate--cysteine ligase.
   
 
 0.972
DGUA_6G011573
Glutathione synthetase.
   
 
  0.972
DGUA_6G015526
Blast:Glutamate--cysteine ligase regulatory subunit.
   
 
  0.972
DGUA_6G019611
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
    
  0.972
DGUA_6G004086
Blast:Cystathionine gamma-lyase.
  
 
 0.952
DGUA_6G003409
Cysteine dioxygenase.
     
  0.950
DGUA_6G019992
Blast:Kynurenine--oxoglutarate transaminase 3.
    
 0.950
DGUA_6G002712
Blast:Probable aspartate aminotransferase, cytoplasmic.
  
 0.927
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (28%) [HD]