Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G017701Blast:RCC1 domain-containing protein 1. (397 aa)    
Predicted Functional Partners:
DGUA_6G009895
Blast:Lysine-specific demethylase 8.
    
 0.993
DGUA_6G015541
Blast:Serine/threonine-protein phosphatase 5.
   
 
 0.623
DGUA_6G014578
Blast:Rab5 GDP/GTP exchange factor.
    
 0.566
DGUA_6G003504
Blast:UPF0587 protein GA18326.
      
 0.548
DGUA_6G003932
Blast:Ran GTPase-activating protein.
   
 0.512
DGUA_6G016296
Blast:E3 SUMO-protein ligase RanBP2.
   
 0.442
DGUA_6G017075
Blast:Putative leucine-rich repeat-containing protein DDB_G0290503.
   
 0.442
DGUA_6G018367
Blast:NudC domain-containing protein 3.
    
  0.417
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (44%) [HD]