Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G006021Blast:Putative transferase CAF17, mitochondrial. (341 aa)    
Predicted Functional Partners:
DGUA_6G018189
Blast:Iron-sulfur cluster assembly 2 homolog, mitochondrial.
  
 
 0.990
DGUA_6G011236
Blast:Iron-sulfur cluster assembly 1 homolog, mitochondrial.
  
 
 0.917
DGUA_6G007427
Cytosolic Fe-S cluster assembly factor NUBP2 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
      
 0.830
DGUA_6G010270
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
    
 0.827
DGUA_6G018513
Blast:Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
   
 
 0.826
DGUA_6G010100
Blast:Protein bcn92; Belongs to the complex I LYR family.
      
 0.815
DGUA_6G015451
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
     
 0.810
DGUA_6G016523
Blast:Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial.
     
 0.796
Las
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      
 0.770
DGUA_6G007697
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
 
  0.765
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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