Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G001524Blast:Aspartyl/asparaginyl beta-hydroxylase. (1034 aa)    
Predicted Functional Partners:
DGUA_6G003896
Blast:BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3.
      
 0.550
DGUA_6G002707
Blast:Origin recognition complex subunit 6.
      
 0.544
DGUA_6G000031
Peptidylprolyl isomerase.
     
 0.507
DGUA_6G002971
Blast:Ryanodine receptor 44F.
   
 
 0.494
DGUA_6G006066
Ig-like domain-containing protein.
   
 
 0.494
DGUA_6G018308
Blast:SRR1-like protein.
      
 0.492
DGUA_6G002160
Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.
      
 0.491
DGUA_6G011259
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
      
 0.482
DGUA_6G015846
Blast:Cyclin-C; Belongs to the cyclin family.
      
 0.480
DGUA_6G003847
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 0.473
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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