Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G013222Blast:D-aspartate oxidase. (344 aa)    
Predicted Functional Partners:
DGUA_6G020098
Serine--pyruvate aminotransferase.
  
 
 0.989
DGUA_6G002612
Blast:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2.
  
 0.987
DGUA_6G006801
Blast:Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.985
DGUA_6G010270
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
    
 0.985
DGUA_6G003611
Blast:Peroxisomal (S)-2-hydroxy-acid oxidase GLO5.
  
 
 0.984
DGUA_6G005554
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
  
 
 0.981
DGUA_6G006225
Blast:Probable low-specificity L-threonine aldolase 2.
    
 0.981
DGUA_6G015451
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.981
DGUA_6G017260
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
  
 
 0.981
DGUA_6G000622
5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.980
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (30%) [HD]