Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G017864Blast:Multiple coagulation factor deficiency protein 2 homolog. (754 aa)    
Predicted Functional Partners:
DGUA_6G009917
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.
   
 0.987
DGUA_6G001978
Blast:DNA polymerase zeta catalytic subunit.
   
 0.951
DGUA_6G013333
Blast:Ubiquitin-40S ribosomal protein S27a.
    
  0.950
DGUA_6G000762
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.950
DGUA_6G004504
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.950
DGUA_6G011881
Blast:Ubiquitin-60S ribosomal protein L40.
    
 0.935
DGUA_6G016961
Blast:Mitotic spindle assembly checkpoint protein MAD2B.
   
 0.922
DGUA_6G006932
Blast:DNA polymerase eta.
  
0.868
DGUA_6G015151
Blast:Polyubiquitin.
    
  0.856
DGUA_6G008901
Blast:Polyubiquitin.
    
  0.856
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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