Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G001995Blast:Tyrosine-protein kinase Drl. (330 aa)    
Predicted Functional Partners:
DGUA_6G003980
Blast:Tyrosine-protein kinase Drl.
    
  0.978
DGUA_6G003977
Blast:Tyrosine-protein kinase Dnt.
    
  0.952
DGUA_6G006560
Blast:Frizzled; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.937
DGUA_6G011082
Blast:Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.937
DGUA_6G007110
Blast:Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.937
DGUA_6G011040
Blast:Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.937
DGUA_6G020396
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.747
DGUA_6G014022
Blast:Probable tyrosyl-DNA phosphodiesterase.
    
   0.600
DGUA_6G002960
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.564
DGUA_6G013815
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.564
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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