Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G018009Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (481 aa)    
Predicted Functional Partners:
DGUA_6G016006
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 0.999
DGUA_6G014211
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
 0.999
DGUA_6G005199
Blast:Bifunctional purine biosynthesis protein PURH.
  
 0.999
DGUA_6G014733
Blast:Adenine phosphoribosyltransferase.
  
 0.998
DGUA_6G018535
Blast:Multifunctional protein ADE2.
 
   
 0.992
DGUA_6G009103
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
     
 0.992
DGUA_6G006654
Blast:Adenosine kinase.
  
 0.991
DGUA_6G000530
Blast:Adenosine kinase.
  
 0.991
DGUA_6G017048
Blast:Adenosine kinase.
  
 0.991
DGUA_6G007276
Blast:Guanylate kinase.
   
 0.988
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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