Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G018038Blast:Protein arginine N-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (376 aa)    
Predicted Functional Partners:
DGUA_6G009190
Blast:Pyridoxine/pyridoxamine 5'-phosphate oxidase.
    
   0.771
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.735
DGUA_6G001020
Blast:rRNA 2'-O-methyltransferase fibrillarin.
   
 
 0.692
DGUA_6G019293
Blast:40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
 0.628
DGUA_6G004150
Blast:40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
 0.628
DGUA_6G019829
Blast:Histone-lysine N-methyltransferase SETD1.
    
 0.583
DGUA_6G005321
Blast:Histone-arginine methyltransferase CARMER; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
   
 0.560
DGUA_6G006503
Blast:H/ACA ribonucleoprotein complex subunit 2-like protein.
   
 0.544
DGUA_6G008282
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.542
DGUA_6G020390
Blast:Bystin.
   
 0.539
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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