Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G002110Blast:Dolichol kinase; Belongs to the protein kinase superfamily. (361 aa)    
Predicted Functional Partners:
DGUA_6G008616
Blast:G1/S-specific cyclin-D2; Belongs to the cyclin family.
   
 0.994
DGUA_6G007313
Blast:NADH-cytochrome b5 reductase 3; Belongs to the cyclin family.
   
 0.993
DGUA_6G001605
Blast:Cyclin-dependent kinase inhibitor 1.
   
 0.986
DGUA_6G014300
Blast:G1/S-specific cyclin-E; Belongs to the cyclin family.
   
 0.977
DGUA_6G019750
Blast:S-phase kinase-associated protein 2.
   
 0.971
DGUA_6G016556
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.965
DGUA_6G008069
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.957
DGUA_6G014549
Blast:Serine/threonine-protein kinase polo.
   
 0.951
DGUA_6G019383
Blast:Retinoblastoma family protein.
   
 0.951
DGUA_6G016388
Blast:Transcription factor E2f.
    
 0.944
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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