Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
DGUA_6G001353Blast:E3 ubiquitin-protein ligase MARCH8. (425 aa)    
Predicted Functional Partners:
DGUA_6G013224
Uncharacterized protein.
   
  
 0.878
DGUA_6G014762
Blast:DnaJ homolog subfamily B member 13.
   
  
 0.872
DGUA_6G005967
Uncharacterized protein.
      
 0.867
DGUA_6G005556
Blast:Ubiquitin-conjugating enzyme E2 J2.
    
 
 0.736
DGUA_6G003592
Blast:Feline leukemia virus subgroup C receptor-related protein 2.
   
  
 0.721
DGUA_6G007867
Blast:WD repeat-containing protein 63.
   
  
 0.706
DGUA_6G020647
Blast:Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.687
DGUA_6G013851
Blast:Radial spoke head 1 homolog.
      
 0.664
DGUA_6G010702
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.621
DGUA_6G014331
Uncharacterized protein.
   
  
 0.603
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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