Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G013198Blast:Interference hedgehog. (888 aa)    
Predicted Functional Partners:
DGUA_6G005508
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.999
DGUA_6G001922
Blast:Protein patched.
    
 0.998
DGUA_6G013769
Blast:Protein smoothened; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.939
DGUA_6G019443
Blast:Casein kinase II subunit beta.
   
  0.899
DGUA_6G018665
Uncharacterized protein.
    
 0.851
DGUA_6G006530
Blast:Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
   
 0.825
DGUA_6G008887
Blast:Protein shifted.
    
 
 0.557
DGUA_6G014307
Blast:Neuroligin-2.
    
 
 0.544
DGUA_6G015585
Blast:Glutamate receptor ionotropic, kainate 2.
    
 0.530
DGUA_6G000548
Blast:Kinesin-like protein costa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.526
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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