DGUA_6G018367 protein (Drosophila guanche) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DGUA_6G018367

Blast:NudC domain-containing protein 3. (292 aa)

Predicted Functional Partners:

Lis-1

0.947

DGUA_6G007609

0.867

DGUA_6G009954

0.733

DGUA_6G001645

0.710

DGUA_6G013564

0.706

DGUA_6G019578

0.695

DGUA_6G000537

0.686

DGUA_6G017427

0.665

DGUA_6G008796

0.643

DGUA_6G016758

0.643

Your Current Organism:

Drosophila guanche

NCBI taxonomy Id: 7266
Other names: D. guanche

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGUA_6G000537	DGUA_6G007609	A0A3B0IYY9	A0A3B0JUF2	Blast:Inner centromere protein.	Blast:Nuclear distribution protein nudE homolog.	0.575
DGUA_6G000537	DGUA_6G018367	A0A3B0IYY9	A0A3B0JMN7	Blast:Inner centromere protein.	Blast:NudC domain-containing protein 3.	0.686
DGUA_6G000537	Lis-1	A0A3B0IYY9	A0A3B0J1S7	Blast:Inner centromere protein.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.	0.619
DGUA_6G001645	DGUA_6G018367	A0A3B0J0D5	A0A3B0JMN7	Blast:Mediator of RNA polymerase II transcription subunit 9.	Blast:NudC domain-containing protein 3.	0.710
DGUA_6G007609	DGUA_6G000537	A0A3B0JUF2	A0A3B0IYY9	Blast:Nuclear distribution protein nudE homolog.	Blast:Inner centromere protein.	0.575
DGUA_6G007609	DGUA_6G008796	A0A3B0JUF2	A0A3B0JWX1	Blast:Nuclear distribution protein nudE homolog.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.524
DGUA_6G007609	DGUA_6G016758	A0A3B0JUF2	A0A3B0KGL7	Blast:Nuclear distribution protein nudE homolog.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.524
DGUA_6G007609	DGUA_6G018367	A0A3B0JUF2	A0A3B0JMN7	Blast:Nuclear distribution protein nudE homolog.	Blast:NudC domain-containing protein 3.	0.867
DGUA_6G007609	Lis-1	A0A3B0JUF2	A0A3B0J1S7	Blast:Nuclear distribution protein nudE homolog.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.	0.998
DGUA_6G008796	DGUA_6G007609	A0A3B0JWX1	A0A3B0JUF2	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Blast:Nuclear distribution protein nudE homolog.	0.524
DGUA_6G008796	DGUA_6G016758	A0A3B0JWX1	A0A3B0KGL7	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.986
DGUA_6G008796	DGUA_6G018367	A0A3B0JWX1	A0A3B0JMN7	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Blast:NudC domain-containing protein 3.	0.643
DGUA_6G008796	Lis-1	A0A3B0JWX1	A0A3B0J1S7	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.	0.861
DGUA_6G009954	DGUA_6G018367	A0A3B0KLS5	A0A3B0JMN7	Blast:Collagen type IV alpha-3-binding protein.	Blast:NudC domain-containing protein 3.	0.733
DGUA_6G013564	DGUA_6G018367	A0A3B0K1R7	A0A3B0JMN7	Blast:Cullin-3-A; Belongs to the cullin family.	Blast:NudC domain-containing protein 3.	0.706
DGUA_6G013564	Lis-1	A0A3B0K1R7	A0A3B0J1S7	Blast:Cullin-3-A; Belongs to the cullin family.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.	0.596
DGUA_6G016758	DGUA_6G007609	A0A3B0KGL7	A0A3B0JUF2	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Blast:Nuclear distribution protein nudE homolog.	0.524
DGUA_6G016758	DGUA_6G008796	A0A3B0KGL7	A0A3B0JWX1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.986
DGUA_6G016758	DGUA_6G018367	A0A3B0KGL7	A0A3B0JMN7	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Blast:NudC domain-containing protein 3.	0.643
DGUA_6G016758	Lis-1	A0A3B0KGL7	A0A3B0J1S7	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.	0.861