Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G013979Blast:Protein MCM10 homolog. (783 aa)    
Predicted Functional Partners:
DGUA_6G008069
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.999
DGUA_6G019341
Blast:Cell division control protein 45 homolog.
   
 0.999
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.997
DGUA_6G011527
DNA helicase; Belongs to the MCM family.
   
 0.997
DGUA_6G011059
DNA helicase; Belongs to the MCM family.
   
 0.996
DGUA_6G018036
DNA helicase; Belongs to the MCM family.
   
 0.996
DGUA_6G003561
DNA helicase; Belongs to the MCM family.
   
 0.995
DGUA_6G003679
Blast:DNA replication factor Cdt1.
   
 0.994
DGUA_6G017555
DNA helicase; Belongs to the MCM family.
   
 0.994
DGUA_6G015928
Blast:Tudor domain-containing protein 1.
   
 0.992
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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