Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G007387Blast:E3 ubiquitin-protein ligase mind-bomb. (1212 aa)    
Predicted Functional Partners:
DGUA_6G015585
Blast:Glutamate receptor ionotropic, kainate 2.
   
 0.987
DGUA_6G016521
Blast:Protein neuralized.
   
 0.978
DGUA_6G012509
Blast:Serine/threonine-protein kinase TBK1.
    
 0.948
DGUA_6G016137
Blast:Inhibitor of nuclear factor kappa-B kinase subunit beta.
    
 0.948
DGUA_6G013297
Blast:Ubiquitin carboxyl-terminal hydrolase CYLD.
    
 0.944
DGUA_6G013333
Blast:Ubiquitin-40S ribosomal protein S27a.
   
 0.933
DGUA_6G015274
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.919
DGUA_6G016240
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
 0.912
DGUA_6G011622
Blast:Gamma-aminobutyric acid receptor-associated protein.
   
 0.887
DGUA_6G019962
Blast:Gamma-aminobutyric acid receptor-associated protein-like 1.
   
 0.887
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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