Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G002728S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling. Acts as a sensor of S-adenosyl-L- methionine to signal methionine sufficiency to mTORC1. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase. (302 aa)    
Predicted Functional Partners:
DGUA_6G018395
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
   
 0.865
DGUA_6G000978
Blast:Glycogenin-1.
   
 0.863
DGUA_6G014712
Blast:DEP domain-containing protein 5.
    
 0.736
DGUA_6G000979
Uncharacterized protein.
   
 0.697
DGUA_6G008150
Blast:Nitrogen permease regulator 3-like protein.
   
 0.646
DGUA_6G010719
Blast:Nitrogen permease regulator 2-like protein.
    
 0.578
DGUA_6G012133
Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
   
 
 0.554
DGUA_6G010211
Blast:Phosphorylase b kinase gamma catalytic chain, liver/testis isoform.
     
 0.478
DGUA_6G009126
Blast:Protein CWC15 homolog.
      
 0.471
DGUA_6G000888
Blast:1,4-alpha-glucan-branching enzyme.
   
 
 0.470
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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