Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G000047Blast:Protein enabled. (694 aa)    
Predicted Functional Partners:
DGUA_6G011174
Blast:Ras-associated and pleckstrin homology domains-containing protein 1.
    
 0.997
DGUA_6G009462
Blast:Tyrosine-protein kinase Abl.
    
 0.997
DGUA_6G004703
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
   
 0.950
DGUA_6G019100
Blast:Lipoma-preferred partner homolog.
    
 0.946
DGUA_6G017010
Blast:Tight junction protein ZO-1; Belongs to the MAGUK family.
    
 0.940
DGUA_6G018709
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.927
DGUA_6G004510
Blast:Tyrosine-protein phosphatase Lar.
    
 
 0.894
DGUA_6G000244
Blast:Roundabout homolog 2.
   
 0.886
DGUA_6G005702
Blast:Wiskott-Aldrich syndrome protein homolog.
   
 0.844
DGUA_6G015556
WH2 domain-containing protein.
   
 0.844
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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