Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G016309Blast:Serine/threonine-protein kinase MARK2. (719 aa)    
Predicted Functional Partners:
DGUA_6G002092
Blast:14-3-3 protein zeta; Belongs to the 14-3-3 family.
    
 0.784
DGUA_6G016337
Blast:14-3-3 protein epsilon; Belongs to the 14-3-3 family.
    
 0.784
DGUA_6G003363
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.720
DGUA_6G015615
Blast:Serine/threonine-protein kinase STK11.
  
 
0.720
DGUA_6G016930
Blast:Kinase suppressor of Ras 2.
  
 
0.716
DGUA_6G010510
Blast:Partitioning defective 3 homolog.
    
 
 0.637
DGUA_6G010736
Blast:Dual specificity mitogen-activated protein kinase kinase dSOR1; Belongs to the protein kinase superfamily.
  
  
0.585
DGUA_6G011346
Blast:Raf homolog serine/threonine-protein kinase phl.
   
  0.555
DGUA_6G002357
Blast:Connector enhancer of kinase suppressor of ras 2.
    
 0.555
DGUA_6G017174
Blast:Tensin-3.
      
 0.549
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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