Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G016331Blast:Ribosome production factor 2 homolog. (240 aa)    
Predicted Functional Partners:
DGUA_6G006543
Blast:COMM domain-containing protein 4.
   
 0.991
DGUA_6G018800
Blast:COMM domain-containing protein 3.
  
 0.990
DGUA_6G015085
Blast:Coiled-coil domain-containing protein 22 homolog.
    
 0.990
DGUA_6G008469
Blast:COMM domain-containing protein 10.
   
 0.989
DGUA_6G000269
Blast:Coiled-coil domain-containing protein 93.
    
 
 0.979
DGUA_6G007412
Blast:Down syndrome critical region protein 3 homolog.
    
 
 0.976
DGUA_6G016546
Blast:GDNF-inducible zinc finger protein 1.
    
 
 0.971
DGUA_6G012841
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.969
DGUA_6G017459
Blast:ADP-ribosylation factor-like protein 6-interacting protein 4.
      
 0.867
DGUA_6G015771
Ig-like domain-containing protein.
    
 0.756
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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