Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G016384DNA polymerase. (1447 aa)    
Predicted Functional Partners:
DGUA_6G004998
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.999
DGUA_6G005965
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 0.999
DGUA_6G014562
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
   
 0.999
DGUA_6G015213
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.998
DGUA_6G017555
DNA helicase; Belongs to the MCM family.
   
 0.997
DGUA_6G003637
Blast:WD repeat and HMG-box DNA-binding protein 1.
   
 
 0.995
DGUA_6G007379
DNA polymerase.
   
0.995
DGUA_6G003561
DNA helicase; Belongs to the MCM family.
   
 0.993
DGUA_6G011059
DNA helicase; Belongs to the MCM family.
   
 0.993
DGUA_6G019341
Blast:Cell division control protein 45 homolog.
   
 0.993
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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