Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G017416Signal peptidase complex subunit 3. (179 aa)    
Predicted Functional Partners:
DGUA_6G009168
Blast:Signal peptidase complex subunit 2.
   
 0.998
DGUA_6G016742
Signal peptidase complex catalytic subunit SEC11.
   
 0.984
DGUA_6G005030
Uncharacterized protein.
   
 0.967
DGUA_6G007816
Blast:Translocation protein SEC63 homolog.
    
 
 0.911
DGUA_6G018873
Blast:Translocation protein SEC63 homolog.
    
 
 0.911
DGUA_6G011261
Mitochondrial inner membrane protease subunit.
   
 0.841
DGUA_6G001374
Blast:Mitochondrial inner membrane protease subunit 2.
   
 0.841
DGUA_6G001914
Blast:Ficolin-1.
      
 0.774
DGUA_6G007056
Blast:Alpha-1,3/1,6-mannosyltransferase ALG2.
   
 
  0.750
DGUA_6G015344
UTP--glucose-1-phosphate uridylyltransferase.
     
  0.734
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (28%) [HD]