Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G016522Blast:Parafibromin. (540 aa)    
Predicted Functional Partners:
DGUA_6G014573
Blast:RNA polymerase-associated protein CTR9 homolog.
   
 0.991
DGUA_6G017182
Blast:Zinc finger protein 254.
   
 0.990
DGUA_6G005311
Blast:WD repeat-containing protein 61.
    
 0.988
DGUA_6G017925
Blast:Another transcription unit protein.
   
 0.971
DGUA_6G002805
Blast:RNA polymerase-associated protein Rtf1.
   
 0.946
DGUA_6G014744
Blast:FACT complex subunit spt16.
   
 0.933
DGUA_6G020145
Blast:RNA polymerase-associated protein Rtf1.
   
 0.920
DGUA_6G018731
Blast:RNA polymerase-associated protein Rtf1.
   
 0.920
DGUA_6G003847
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.915
DGUA_6G001812
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.910
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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