Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G016542Blast:Protein NASP homolog. (528 aa)    
Predicted Functional Partners:
DGUA_6G007171
Blast:Histone chaperone asf1.
   
 
 0.975
DGUA_6G017970
Histone acetyltransferase type B catalytic subunit.
   
 
 0.974
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.923
DGUA_6G001435
Blast:Aminoacyl tRNA synthase complex-interacting multifunctional protein 1.
    
 
 0.921
Caf1
Blast:Probable histone-binding protein Caf1.
   
 
 0.907
DGUA_6G016763
Blast:Probable histone-binding protein Caf1.
   
 
 0.907
DGUA_6G014744
Blast:FACT complex subunit spt16.
   
 
 0.856
DGUA_6G003737
Blast:Pre-mRNA-processing factor 19.
      
 0.780
DGUA_6G005505
Blast:Histone RNA hairpin-binding protein.
   
  
 0.777
DGUA_6G016540
Uncharacterized protein.
      
 0.771
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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