Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G013993Blast:Glycoprotein endo-alpha-1,2-mannosidase. (493 aa)    
Predicted Functional Partners:
DGUA_6G013978
Blast:GMP synthase.
  
 
 0.886
DGUA_6G013277
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.793
DGUA_6G010798
Uncharacterized protein.
   
 
 0.727
DGUA_6G003601
Blast:Ribonucleoside-diphosphate reductase subunit M2.
   
 
 0.727
DGUA_6G011614
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
    
 0.723
DGUA_6G002530
Blast:Fukutin-related protein.
   
  0.715
DGUA_6G014733
Blast:Adenine phosphoribosyltransferase.
  
 
 0.710
DGUA_6G014211
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
 
 0.705
DGUA_6G015585
Blast:Glutamate receptor ionotropic, kainate 2.
    
 0.691
DGUA_6G011107
Blast:Protein FAM57B.
    
 
 0.688
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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