Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G002136Blast:Putative gamma-glutamylcyclotransferase CG2811. (154 aa)    
Predicted Functional Partners:
DGUA_6G016374
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
     
  0.581
DGUA_6G007032
Dihydrolipoyl dehydrogenase.
    
 0.442
DGUA_6G006839
Blast:Thioredoxin reductase 2, mitochondrial.
    
 0.442
DGUA_6G019460
Blast:Thioredoxin reductase 1, mitochondrial.
    
 0.442
DGUA_6G019461
Blast:Thioredoxin reductase 1, mitochondrial.
    
 0.442
DGUA_6G019529
Blast:Dual specificity mitogen-activated protein kinase kinase 6.
      
 0.428
DGUA_6G013775
Blast:Stress-induced-phosphoprotein 1.
      
 0.424
DGUA_6G011545
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
     
  0.401
DGUA_6G016304
Blast:Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate.
     
  0.401
DGUA_6G013795
Blast:Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase.
     
  0.401
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (30%) [HD]