Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G016875CHK domain-containing protein. (415 aa)    
Predicted Functional Partners:
DGUA_6G016874
CHK domain-containing protein.
   
    0.964
DGUA_6G016876
CHK domain-containing protein.
   
    0.576
DGUA_6G016163
Blast:Short-chain specific acyl-CoA dehydrogenase, mitochondrial.
      
 0.546
DGUA_6G003836
Blast:Methylglutaconyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.
      
 0.438
DGUA_6G005428
Blast:Aldehyde dehydrogenase X, mitochondrial; Belongs to the aldehyde dehydrogenase family.
      
 0.426
DGUA_6G007544
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.423
DGUA_6G013949
CHK domain-containing protein.
  
   
0.419
DGUA_6G006729
Blast:Centrosome-associated protein CEP250.
  
     0.404
DGUA_6G000028
Blast:Protein unzipped.
  
     0.400
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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