Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G014432Blast:Protein son of sevenless. (1595 aa)    
Predicted Functional Partners:
DGUA_6G001289
Blast:Protein E(Sev)2B.
    
 0.999
DGUA_6G007994
Blast:SHC-transforming protein 1.
    
 0.998
DGUA_6G003161
Receptor protein-tyrosine kinase.
    
 0.997
DGUA_6G017167
Uncharacterized protein.
    
 0.996
DGUA_6G020836
Blast:Protein sevenless.
    
 0.973
DGUA_6G020366
Blast:Tyrosine-protein phosphatase corkscrew.
    
 0.966
DGUA_6G020367
Uncharacterized protein.
    
 0.966
DGUA_6G003714
Tyrosine-protein kinase.
    
 0.941
DGUA_6G011914
Blast:Cytoplasmic protein NCK1.
    
 0.936
DGUA_6G019685
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
 0.934
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.