Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G003386Blast:Probable lysine-specific demethylase 4A. (491 aa)    
Predicted Functional Partners:
DGUA_6G017006
Blast:JmjC domain-containing histone demethylation protein 1.
   
 
 0.812
DGUA_6G014526
Blast:Possible lysine-specific histone demethylase 1.
   
 0.800
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.794
DGUA_6G017171
Blast:Lysine-specific demethylase 3B.
     
 0.783
DGUA_6G021251
Histone H3; Belongs to the histone H3 family.
    
 0.773
DGUA_6G013685
Histone H3; Belongs to the histone H3 family.
    
 0.722
DGUA_6G004249
Uncharacterized protein.
    
   0.712
DGUA_6G001283
Blast:Histone H3-like centromeric protein cid.
    
 0.661
DGUA_6G000353
Blast:Myeloid differentiation primary response protein MyD88.
    
 0.635
DGUA_6G012682
Blast:Heterochromatin protein 1.
    
 
 0.630
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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