Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G017099Blast:Mitochondrial glutamate carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)    
Predicted Functional Partners:
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
   0.644
DGUA_6G012520
Blast:Alpha-aminoadipic semialdehyde synthase, mitochondrial.
   
  
 0.577
DGUA_6G014774
Blast:Protein encore.
      
 0.539
DGUA_6G017098
Blast:Mitochondrial glutamate carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
     
  0.494
DGUA_6G017687
MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 
 0.462
DGUA_6G019384
Blast:HEAT repeat-containing protein 6.
      
 0.459
DGUA_6G003239
Blast:Mitochondrial import inner membrane translocase subunit Tim10.
   
  
 0.440
DGUA_6G020041
Arginase.
      
 0.429
DGUA_6G006303
Blast:Calcium-activated potassium channel slowpoke.
      
 0.428
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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