Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G017460Blast:Structural maintenance of chromosomes protein 1A; Belongs to the eukaryotic initiation factor 4E family. (223 aa)    
Predicted Functional Partners:
DGUA_6G011975
Blast:Eukaryotic translation initiation factor 4E-binding protein 2.
    
 0.814
DGUA_6G004707
Blast:Eukaryotic initiation factor 4A; Belongs to the DEAD box helicase family.
   
 0.809
DGUA_6G018293
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
    
 0.759
DGUA_6G010180
Blast:Torsin-like protein.
    
 0.758
DGUA_6G015954
Blast:Nuclear cap-binding protein subunit 1.
    
 0.758
DGUA_6G012105
Blast:Etoposide-induced protein 2.4.
    
  0.755
DGUA_6G001901
Blast:Eukaryotic translation initiation factor 4 gamma 2.
   
 0.742
DGUA_6G017835
Blast:Eukaryotic translation initiation factor 4 gamma 1.
   
 0.742
DGUA_6G019137
Blast:Eukaryotic translation initiation factor 4 gamma 1.
   
 0.742
DGUA_6G013323
Blast:Putative ATP-dependent RNA helicase me31b; Belongs to the DEAD box helicase family.
   
 0.669
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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