Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G006625Blast:Alsin. (640 aa)    
Predicted Functional Partners:
DGUA_6G001442
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.997
DGUA_6G012196
Blast:Enolase.
  
 0.997
DGUA_6G015040
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.996
DGUA_6G017906
Blast:Transketolase-like protein 2.
  
 0.993
DGUA_6G002711
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.992
DGUA_6G001851
Blast:L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.991
DGUA_6G000611
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.990
DGUA_6G018123
Blast:Fructose-bisphosphate aldolase.
  
 
 0.987
DGUA_6G018119
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
  
 
 0.987
DGUA_6G005489
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.987
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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