Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G017222Blast:Geranylgeranyl transferase type-2 subunit alpha. (505 aa)    
Predicted Functional Partners:
DGUA_6G014254
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.999
DGUA_6G003273
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
   
 0.994
DGUA_6G016062
Blast:Ras-related protein Rab-1A.
    
 0.894
DGUA_6G010974
Blast:Ras-related protein Rab-39A.
    
 0.866
DGUA_6G007577
Blast:Ras-related protein Rab-34.
    
 0.857
DGUA_6G003946
Blast:Ras-related protein Rab-9A.
    
 0.854
DGUA_6G012745
Blast:Ras-related protein Rab6.
    
 0.784
DGUA_6G012673
Blast:Ras-related protein Rab-5C.
    
 0.752
DGUA_6G012666
Blast:Ras-related protein Rab-5A.
    
 0.752
DGUA_6G009949
Blast:Ras-related protein Rab-43.
    
 0.748
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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