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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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gene co-occurrence
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DGUA_6G018294Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (189 aa)    
Predicted Functional Partners:
DGUA_6G005599
Blast:Thioredoxin-dependent peroxide reductase, mitochondrial.
   
 0.977
DGUA_6G011352
Blast:Peroxiredoxin 1.
   
 0.971
Urm1
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]
    
 0.970
DGUA_6G009855
Blast:Peroxiredoxin-4.
   
 0.946
DGUA_6G010058
Blast:Thioredoxin, mitochondrial.
   
 0.943
DGUA_6G009605
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.890
DGUA_6G006523
Blast:Thioredoxin-T.
   
 0.846
DGUA_6G020054
Blast:Thioredoxin-T.
   
 0.846
DGUA_6G004187
Thioredoxin; Belongs to the thioredoxin family.
   
 0.846
DGUA_6G001685
Blast:Peroxiredoxin-6.
   
 0.836
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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