DGUA_6G010543 protein (Drosophila guanche) - STRING interaction network

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Score

DGUA_6G010543

Blast:E3 SUMO-protein ligase PIAS1. (156 aa)

Predicted Functional Partners:

DGUA_6G017305

0.942

DGUA_6G012047

0.899

DGUA_6G012616

0.899

DGUA_6G004984

0.864

DGUA_6G007986

0.853

DGUA_6G008743

0.841

DGUA_6G008742

0.841

DGUA_6G003936

0.837

DGUA_6G010923

0.823

DGUA_6G000762

0.756

Your Current Organism:

Drosophila guanche

NCBI taxonomy Id: 7266
Other names: D. guanche

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGUA_6G000762	DGUA_6G003936	A0A3B0JJA1	A0A3B0KBF1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.742
DGUA_6G000762	DGUA_6G004984	A0A3B0JJA1	A0A3B0JXA2	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Blast:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L.	0.942
DGUA_6G000762	DGUA_6G008742	A0A3B0JJA1	A0A3B0KL35	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Blast:SUMO-conjugating enzyme UBC9.	0.786
DGUA_6G000762	DGUA_6G008743	A0A3B0JJA1	A0A3B0JWR9	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Blast:SUMO-conjugating enzyme UBC9-A.	0.786
DGUA_6G000762	DGUA_6G010543	A0A3B0JJA1	A0A3B0JRA1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Blast:E3 SUMO-protein ligase PIAS1.	0.756
DGUA_6G000762	DGUA_6G010923	A0A3B0JJA1	A0A3B0K4B7	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.858
DGUA_6G000762	DGUA_6G012047	A0A3B0JJA1	A0A3B0JEZ1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Blast:SUMO-conjugating enzyme UBC9-B; Belongs to the ubiquitin-conjugating enzyme family.	0.786
DGUA_6G000762	DGUA_6G012616	A0A3B0JJA1	A0A3B0K425	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Blast:SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	0.786
DGUA_6G003936	DGUA_6G000762	A0A3B0KBF1	A0A3B0JJA1	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.742
DGUA_6G003936	DGUA_6G004984	A0A3B0KBF1	A0A3B0JXA2	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Blast:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L.	0.968
DGUA_6G003936	DGUA_6G007986	A0A3B0KBF1	A0A3B0JVB4	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Blast:E3 SUMO-protein ligase NSE2.	0.420
DGUA_6G003936	DGUA_6G008742	A0A3B0KBF1	A0A3B0KL35	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Blast:SUMO-conjugating enzyme UBC9.	0.667
DGUA_6G003936	DGUA_6G008743	A0A3B0KBF1	A0A3B0JWR9	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Blast:SUMO-conjugating enzyme UBC9-A.	0.667
DGUA_6G003936	DGUA_6G010543	A0A3B0KBF1	A0A3B0JRA1	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Blast:E3 SUMO-protein ligase PIAS1.	0.837
DGUA_6G003936	DGUA_6G010923	A0A3B0KBF1	A0A3B0K4B7	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.986
DGUA_6G003936	DGUA_6G012047	A0A3B0KBF1	A0A3B0JEZ1	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Blast:SUMO-conjugating enzyme UBC9-B; Belongs to the ubiquitin-conjugating enzyme family.	0.667
DGUA_6G003936	DGUA_6G012616	A0A3B0KBF1	A0A3B0K425	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Blast:SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	0.667
DGUA_6G004984	DGUA_6G000762	A0A3B0JXA2	A0A3B0JJA1	Blast:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.942
DGUA_6G004984	DGUA_6G003936	A0A3B0JXA2	A0A3B0KBF1	Blast:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.968
DGUA_6G004984	DGUA_6G007986	A0A3B0JXA2	A0A3B0JVB4	Blast:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L.	Blast:E3 SUMO-protein ligase NSE2.	0.967