Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G001221Blast:POU domain, class 6, transcription factor 2. (1373 aa)    
Predicted Functional Partners:
DGUA_6G010932
POU domain protein.
   
 
 0.658
DGUA_6G018525
Blast:DNA-directed RNA polymerases I, II, and III subunit RPABC2.
     
 0.479
DGUA_6G004525
Blast:Brain-specific homeobox protein.
   
 0.475
DGUA_6G019742
Blast:snRNA-activating protein complex subunit 4.
    
  0.472
DGUA_6G019757
Blast:Zinc finger matrin-type protein CG9776.
      
 0.465
DGUA_6G002918
Blast:Protein Optix.
   
  
 0.435
DGUA_6G001959
Blast:Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.
     
 0.427
DGUA_6G007806
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
     
 0.426
DGUA_6G016278
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
     
  0.424
DGUA_6G004166
Blast:Transcription initiation factor TFIID subunit 11.
     
  0.424
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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