Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
DGUA_6G003054Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (100 aa)    
Predicted Functional Partners:
DGUA_6G000297
Blast:Probable protein transport protein Sec61 subunit gamma.
   
 0.999
DGUA_6G020992
Blast:Protein transport protein Sec61 subunit alpha isoform 2.
   
 0.999
DGUA_6G001416
Uncharacterized protein.
   
 0.995
DGUA_6G004141
Blast:Translocon-associated protein subunit gamma.
   
 0.995
DGUA_6G007816
Blast:Translocation protein SEC63 homolog.
    
 
 0.991
DGUA_6G009323
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
 0.991
DGUA_6G018873
Blast:Translocation protein SEC63 homolog.
    
 
 0.991
DGUA_6G004875
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]
   
 
 0.975
DGUA_6G004112
Blast:Translocation protein SEC62.
   
 
 0.968
DGUA_6G020401
60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.
   
 
 0.957
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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