Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G010688Blast:C-myc promoter-binding protein. (1691 aa)    
Predicted Functional Partners:
DGUA_6G011138
Blast:Ras-related protein Rab-10.
    
 0.875
DGUA_6G018257
Blast:Ras-related protein Rab-11A.
    
 
 0.801
DGUA_6G000481
Blast:Rap1 GTPase-GDP dissociation stimulator 1-B.
      
 0.728
DGUA_6G018946
Blast:F-box/LRR-repeat protein 4.
      
 0.692
DGUA_6G007923
Blast:Ras-related protein Rab-8A.
    
 0.683
DGUA_6G006258
Blast:Ras-related protein Rab-8A.
    
 0.683
DGUA_6G003273
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
 0.640
DGUA_6G011546
Blast:MAP kinase-activating death domain protein.
    
   0.635
DGUA_6G004459
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
     
  0.621
DGUA_6G014201
Blast:Glutaryl-CoA dehydrogenase, mitochondrial.
      
 0.618
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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