Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G016154Blast:ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. (685 aa)    
Predicted Functional Partners:
DGUA_6G015184
Blast:AFG3-like protein 2.
  
  
 0.864
DGUA_6G002299
Blast:ATP-dependent zinc metalloprotease YME1 homolog.
  
  
 0.843
DGUA_6G020337
Blast:Paraplegin.
  
  
 0.834
DGUA_6G014001
Blast:Thioredoxin domain-containing protein 17.
      
 0.831
DGUA_6G006926
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
  
 0.830
DGUA_6G005735
Blast:Zinc finger protein 330 homolog.
    
   0.801
DGUA_6G007166
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.
  
 
 0.788
DGUA_6G018727
Lon protease homolog; Belongs to the peptidase S16 family.
  
 
 0.788
DGUA_6G000622
5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
   
 0.779
DGUA_6G004638
Blast:60 kDa heat shock protein homolog 2, mitochondrial; Belongs to the chaperonin (HSP60) family.
  
 0.774
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (54%) [HD]