Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
DGUA_6G010892E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (739 aa)    
Predicted Functional Partners:
DGUA_6G010895
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
 
     0.924
DGUA_6G013301
Blast:E3 ubiquitin-protein ligase HECTD1.
   
  
 0.647
DGUA_6G018573
Blast:Protein ovo.
    
 
 0.618
DGUA_6G015870
Blast:Cullin-5; Belongs to the cullin family.
   
    0.581
DGUA_6G012080
Blast:Dorsal-related immunity factor Dif.
      
 0.551
DGUA_6G014456
Blast:Apoptosis 1 inhibitor.
   
 
 0.538
DGUA_6G017203
Blast:Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.493
DGUA_6G003687
Blast:Mitochondrial intermediate peptidase.
      
 0.467
DGUA_6G012393
Blast:Blastoderm-specific protein 25D.
      
 0.442
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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