STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G001477Blast:Kunitz-type serine protease inhibitor textilinin-3. (120 aa)    
Predicted Functional Partners:
DGUA_6G014880
NEDD8-activating enzyme E1 regulatory subunit.
    
 0.890
DGUA_6G007782
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.797
DGUA_6G009541
Blast:JNK-interacting protein 1.
   
 
 0.729
DGUA_6G005014
Blast:Nicastrin.
    
 0.725
DGUA_6G011915
Blast:Integral membrane protein 2B.
   
 0.703
DGUA_6G008639
Glyceraldehyde-3-phosphate dehydrogenase.
     
 0.681
DGUA_6G002506
Glyceraldehyde-3-phosphate dehydrogenase.
     
 0.663
DGUA_6G009191
Blast:Atrial natriuretic peptide-converting enzyme.
    
 0.640
DGUA_6G008020
Blast:Peptidyl-prolyl cis-trans isomerase D.
    
   0.636
DGUA_6G018095
Calreticulin.
    
 
 0.623
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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